KEGG   Homo sapiens (human): 1791
Entry
1791              CDS       T01001                                 
Symbol
DNTT, TDT
Name
(RefSeq) DNA nucleotidylexotransferase
  KO
K00977  DNA nucleotidylexotransferase [EC:2.7.7.31]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03450  Non-homologous end-joining
hsa04640  Hematopoietic cell lineage
Network
nt06506  Double-strand break repair
  Element
N01445  Non-homologous end-joining
N01467  V(D)J recombination
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03450 Non-homologous end-joining
    1791 (DNTT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    1791 (DNTT)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    1791 (DNTT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.31  DNA nucleotidylexotransferase
     1791 (DNTT)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    X-family DNA polymerases
     1791 (DNTT)
SSDB
Motif
Pfam: DNA_pol_B_thumb DNA_pol_lambd_f BRCT NTP_transf_2 DNA_pol_B_palm HHH_8 LIG3_BRCT
Other DBs
NCBI-GeneID: 1791
NCBI-ProteinID: NP_004079
OMIM: 187410
HGNC: 2983
Ensembl: ENSG00000107447
UniProt: P04053
Structure
Position
10:96304434..96338564
AA seq 509 aa
MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMT
GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRQFERDLRRYATHERKMILDNHALYDKT
KRIFLKAESEEEIFAHLGLDYIEPWERNA
NT seq 1530 nt   +upstreamnt  +downstreamnt
atggatccaccacgagcgtcccacttgagccctcggaagaagagaccccggcagacgggt
gccttgatggcctcctctcctcaagacatcaaatttcaagatttggtcgtcttcattttg
gagaagaaaatgggaaccacccgcagagcgttcctcatggagctggcccgcaggaaaggg
ttcagggttgaaaatgagctcagtgattctgtcacccacatcgtagcagagaacaactcg
ggttcggatgttctggagtggcttcaagcacagaaagtacaagtcagctcacaaccagag
ctcctcgatgtctcctggctgatcgaatgcataagagcagggaaaccggtggaaatgaca
ggaaaacaccagcttgttgtgagaagagactattcagatagcaccaacccaggccccccg
aagactccaccaattgctgtacaaaagatctcccagtatgcgtgtcagagaagaaccact
ttaaacaactgtaaccagatattcacggatgcctttgatatactggctgaaaactgtgag
tttagagaaaatgaagactcctgtgtgacatttatgagagcagcttctgtattgaaatct
ctgccattcacaatcatcagtatgaaggacacagaaggaattccctgcctggggtccaag
gtgaagggtatcatagaggagattattgaagatggagaaagttctgaagttaaagctgtg
ttaaatgatgaacgatatcaatccttcaaactctttacttctgtatttggagtggggctg
aagacttctgagaagtggttcaggatgggtttcagaactctgagtaaagtaaggtcggac
aaaagcctgaaatttacacgaatgcagaaagcaggatttctgtattatgaagaccttgtc
agctgtgtgaccagggcagaagcagaggccgtcagtgtgctggttaaagaggctgtctgg
gcatttcttccggatgctttcgtcaccatgacaggagggttccggaggggtaagaagatg
gggcatgatgtagattttttaattaccagcccaggatcaacagaggatgaagagcaactt
ttacagaaagtgatgaacttatgggaaaagaagggattacttttatattatgaccttgtg
gagtcaacatttgaaaagctcaggttgcctagcaggaaggttgatgctttggatcatttt
caaaagtgctttctgattttcaaattgcctcgtcaaagagtggacagtgaccagtccagc
tggcaggaaggaaagacctggaaggccatccgtgtggatttagttctgtgcccctacgag
cgtcgtgcctttgccctgttgggatggactggctcccggcagtttgagagagacctccgg
cgctatgccacacatgagcggaagatgattctggataaccatgctttatatgacaagacc
aagaggatattcctcaaagcagaaagtgaagaagaaatttttgcgcatctgggattggat
tatattgaaccgtgggaaagaaatgcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
3D Structure (2)   
   PDB (2)   
Protein domain (7)   
   Pfam (7)   
All databases (53)   

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